In order to study the temperature and humidity coupling characteristics and slope stability of a certain slope in Nanning Guangxi under different rainfall conditions(average rainfall front rainfall center front rainfall and post front rainfall).The finite element calculation of Geo-slope 2012，a famous geotechnical software in Canada，is carried out.The results show that：Under rainfall condition，the pore pressure and volume water content of the surface layer of the slope reach the maximum at first，and then develop to the depth of the slope gradually.After the rainfall，the pore pressure and the volume water content of the surface layer of the slope decrease rapidly.The order of pore pressure and volume water content in the surface layer of slope soil is as follows：posterior front rainfall ≥ center front rainfall ≥ average rainfall ≥ front rainfall.The order of pore pressure and volume water content in the deep layer is as follows：posterior front rainfall ≤ average rainfall ≤ center front rainfall ≤ front rainfall.After the end of rainfall，the order of pore pressure and volume water content in slope soil is as follows：posterior front rainfall ≥ average rainfall ≥ center front rainfall ≥ front rainfall.The total temperature field in the slope is consistent with the climate change，which increases first and then decreases，and the range of temperature change in the slope is smaller than that in the surface of the slope，and the temperature variation of the lower monitoring surface is smaller than that of the upper monitoring surface and the central monitoring surface.The safety coefficient gradually decreases with time in the rainfall process，and keeps constant after the rain.The safety coefficient of different rainfall types in the early period of rainfall is：the rear front type more than average type center type or more forward type，and the final safety factor tends to a fixed value.