In order to investigate the effect of economic development on the water quality of local river，in this paper，the water quality of Lishui River was monitored for five years.The single factor evaluation method showed that the water quality of Foling monitoring section was mainlyⅡ，the water quality of Dengjiazhou was mainly Ⅲ，both sections of Lishui River could meet the requirements of water function zoning.The comprehensive pollution index method showed that the indexes of Foling monitoring section were lower than those of Dengjiazhou monitoring section in each year from 2011 to 2015，but the comprehensive pollution index of both sections showed an upward trend.The ranking of pollution index(Pi j)and pollution share rate(Ki)of each pollutant showed that the main pollutant targets of both sections were mainly organic pollutants，such as total nitrogen，chemical oxygen demand(COD)，permanganate index and five days' biochemical oxygen(BOD5).According to the result of water quality monitoring and evaluation of Lishui River，the pollution controlling measures were proposed，which could provide effective basis for river management of Lishui River.