In order to study the effect of the stacking width at the top of the slope，the minimum distance between the load range and the slope，and the effect of the size of the load on the slope stability，sensitivity analysis of stability of stacking slope was carried out by using large-scale finite element software GTS-NX combined with orthogonal test design method，the calculation results showed that the stability coefficient of the slope reduced with the width of the stack at the top of the slope widening，the minimum distance between the load range and the slope decreasing and loading load increasing，through the range analysis the three factors，Its sensitivity from large to small were uniform heap size(q)>The width of the load(B)>The minimum distance from the slope to the load(d).