Data of hydrology, water quality, water resources were analyzed for Xunwu River of Dongjiang River's source, and problems existing in process of water resources development and utilization in the river basin were analyzed from three aspects of time and space changes of water resources, water quality situation and water resources development and utilization. Results showed that the problems were as following: time warp of water supply and water use, supervision of water conservancy project not reaching the designated goal, low in storage capacity of engineering, large proportion of agricultural water, water quality of parts of water function area not up to standard, amount of water use exceed standard, and so on. Measures and suggestions of reasonable development and utilization of water resources were put forward from aspects of industrial structure adjustment, water pollution prevention, water conservancy project management and supervision, total water control, which providing references in rational development, optimal allocation, reasonable scheduling and comprehensive control of water resources in this river basin and the whole Dongjiang River basin in the future.